AJDRAJNR - American Journal of Neuroradiology

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FIG 1. Human vertebrobasilar aneurysm embolized with platinum coils.

A, Gross photograph showing thin membranous tissue at the neck with coil loops that are visible through the membrane.

B, Section of the vertebrobasilar aneurysm stained with H&E (magnification 100x). The photomicrograph shows hypocellular, amorphous tissue in the dome.

C, Section of the aneurysm stained with H&E (magnification 60x). This photomicrograph shows a large area of poorly organized thrombus in the aneurysm dome.

D, Section stained with H&E (magnification 20x). A photomicrograph showing a thin layer of hypocellular tissue covering the neck of aneurysm.

E, Immunofluorescent double stain of the vertebrobasilar aneurysm, with antibodies for SMA (red) and vimentin (green) (magnification 20x; oil). This photomicrograph shows scattered, sparse cells within the aneurysm dome, which are positive for vimentin, but negative for SMA.

F, Stained with Masson trichrome (magnification 60x). It reveals that collagen deposition was absent in the aneurysm.





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