AJDRAJNR - American Journal of Neuroradiology

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FIG 3. Swine aneurysm embolized with platinum coils.

A, Gross photograph showing a smooth, thick membrane completely covering the neck. Coil loops are not visible through this membrane.

B, Section of the swine aneurysm stained with H&E (magnification 60x). The photomicrograph shows diffuse, attenuated chronic inflammatory tissue within the aneurysm dome.

C, Stained with H&E (magnification 60x). This photomicrograph shows extensive, attenuated, fibrous tissue within the dome, which is associated with rich neovessels.

D, Section stained with Masson trichrome (magnification 60x). A photomicrograph shows diffuse, attenuated, abundant, collagen fibers within the aneurysm dome.

E, Section stained with H&E (magnification 40x). A photomicrograph of this stained section shows a thick layer of hypercellular tissue along aneurysm neck.

F, Immunofluorescent double stain with antibodies for SMA (red) and vimentin (green) (magnification = 20x; oil). This photomicrograph reveals the attenuated cells at neck of aneurysm are positive for both SMA and vimentin, which indicates classic neointimal formation.





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