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FIG 3. Statistical parametric maps show comparison of patients with early-onset AD and those with late-onset AD. Highlighted areas are regions of significant decreased density in patients with early-onset AD compared with those with late-onset AD at a threshold of P < .001, uncorrected. The gray matter densities in the bilateral precuneus, left parietal cortex, right middle temporal gyrus, and left fusiform gyrus were lower in the early-onset group than in the late-onset group. L indicates left; R, right.
