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FIG 2. Case 2.
A–C, Postmortem axial (A and B) and coronal (C) T2-weighted MR images show cortical laminar hyperintensities in the frontal lobes (B and C, arrows). Hyperintensities are also seen in the deep and subcortical white matters.
D, Boxed area in panel C shows laminar hyperintensities in the deep layers of the cerebral cortex (arrowheads).
E, The hematoxylin and eosin-stained section corresponding to panel D shows laminar pallor of the deep layers of the cerebral cortex (arrowheads). U-fibers are well preserved in this case (D and E, arrows).
F, Histologic findings of the arrowhead area panel E shows spongy changes of the neuropil, pyknotic, and shrunken neurons (arrowheads) and Alzheimer type II astrocytes (arrows). (Hematoxylin and eosin x100.)
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