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FIG 2. Changes in GFAP immunostaining and in vivo Cho/Cr and MI/Cr after SIV infection. Levels of GFAP were determined by immunohistochemistry. Levels of Cho/Cr and MI/Cr are from 1H MR spectroscopic measurements previously reported (1). Peaks of all three measures were attained at 11–12 days, coincident with peak viremia. Measures then diverge, with GFAP immunostains returning to normal levels by 14 dpi (DPI), MI/Cr remaining elevated, and Cho/Cr decreasing to subnormal levels at 25–27 dpi. Error bars = SEM.
