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FIG 4. In vivo spectrum of control frontal cortex was obtained at 1.5 T (top) and collected with PROBE-P (11) (point-resolved [PRESS] sequence with chemical shift selective [CHESS] water suppression [12, 13], TR/TE/NEX = 3000/35/128). The animal was euthanized, a frontal cortex sample was removed, and metabolites were extracted for ex vivo high-resolution 1H MR study at 14.1 T (bottom). Gln = glutamine, Glu = glutamate, GPC = glycerophosphorylcholine, PC = phosphorylcholine, tau = taurine.
