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FIG 1. Color-coded SPMt maps superimposed on a high-spatial-resolution T1-weighted image showing relative cortical activations during a simple motor task with the dominant, functionally normal right hand in patients with clinically isolated syndromes suggestive of MS that did not evolve to definite MS compared with those who did (random effect analysis, between-group comparison, corrected P value < .05).
A, Ipsilateral paracentral lobule.
B, Contralateral primary somatomotor cortex and supplementary motor area.
C, Ipsilateral cerebellar hemisphere.
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