AJDRAJNR - American Journal of Neuroradiology

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FIG 1. Images obtained in a 54-year-old man with biopsy-proven radiation necrosis after receiving radiation and chemotherapy for anaplastic oligodendroglioma.

A, Gadolinium-enhanced T1WI image shows an irregular ring-enhancing lesion with mass effect.

B, DWI image obtained at the same level as A shows a mixed SI pattern (arrowheads), with marked hypointensity (arrow), which is typical for radiation necrosis. Radiation necrosis may have a variety of SI patterns on DWI images, reflecting the development of necrosis. Marked DWI hypointensity is probably attributable to liquefactions in late-stage necrosis.

C, ADC map, which corresponds to B, shows a mixed SI pattern, with a markedly high ADC value (arrow).

D and E, Histopathological specimens (hematoxylin-eosin, x20 [D], x40 [E]) show total parenchymal necrosis with hemorrhage. No evidence of viable tumor cells was found.





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