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FIG 9. False-negative CJD.
A, Axial DWI (poor windows, film cohort) in a 65-year-old man with definite sCJD retrospectively shows subtle hyperintensity of bilateral caudate heads and anterior putamina. Medial and dorsal thalami are subtly abnormal but more diffusely than is typical of CJD. Insular cortex may be pathologically hyperintense or normal.
B, Even in retrospect, calling an abnormality on corresponding FLAIR image (mildly motion degraded) is difficult.
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