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FIG 2. Analysis of 1000 individuals evaluated for 60% diameter carotid stenosis using carotid angiography, is from data generated using the simulation described in the text. Prevalence is taken to be 30%, and the data from Table 3 are used to estimate outcomes, assuming these data are independent of prevalence. Of the 300 individuals with stenosis, 24 (8%) were false-negative (FN), and of the 700 individuals without stenosis, 21 (3%) were false-positive (FP). The overall misclassification rate is approximately 4%. TP indicates, true-positive; TN, indicates true-negative.