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FIG 1. A representative example of a patient with a right hemispheric glioblastoma. ROIs placed in white matter regions encompassing corticospinal and corticopontine tracts both immediately adjacent to the tumor and in the contralateral hemisphere were interrogated for quantitation of FA and for evaluation of the FDi. Adjacent to the tumor, the number of fibers passing through the region (A) can be seen to be markedly fewer than in the contralateral region (C). The 2 ROIs are displayed without fibers in (B). In this case, peritumoral FA was 0.45, compared with 0.65 in the contralateral normal-appearing region. FDi was reduced from 5.38 in the contralateral white matter to 3.11 in the peritumoral white matter. Note the fiber colors themselves have no specific interpretation. Different colors are assigned to each fiber path as an aid to visualization.
