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FIG 5. A 64-year-old man with total removal surgery for metastatic brain tumor, 30-Gy whole brain irradiation, and 15-Gy stereotactic radiosurgery (patient 5). The indices from only the left hemisphere were calculated because the right hemisphere had image distortion caused by the surgical procedure.
A, Axial T2-weighted images (TR/effective/TE/echo train length, 4000 ms/95 ms/18) at 4 (group 2; left), 8 (group 3, middle), and 12 months (group 4, right) following completion of radiation therapy show no abnormal intensity change in WM. At 12 months, slight increase in subarachnoid space of the right hemisphere is shown.
B, Isotropic ADC maps at 4 (left), 8 (middle), and 12 months (right) after completion of radiation therapy. Mean isotropic ADC values were 0.780, 0.707, and 0.720 (x10–3 mm2/s), respectively.
C, FA maps at 4 (left), 8 (middle), and 12 months (right) after completion of radiation therapy. Mean FA values were 0.32, 0.35, and 0.37, respectively. At 4 months after completion of radiation therapy, the mean FA value decreased and mean isotropic ADC value increased in comparison with the averages of mean FA value (0.38; SD = 0.02) and the mean isotropic ADC value (0.692; SD = 0.014) of the controls. The change of the indices appeared to resolve with time.
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