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Fig 1. A 61-year-old male patient with right hemiparesis imaged at 2.3 hours and 3 days. Abnormal areas are outlined on CBV (A), CBF (B), and follow-up CT (C) images. After coregistration, we defined 3 regions on CBF maps (D): region 1 (red), "infarct core"abnormal on CBV, CBF, and follow-up CT images; region 2 (blue), "penumbra that infarcts"normal on CBV but abnormal on CBF and follow-up CT images; and region 3 (green) "penumbra that recovers"abnormal on CBF but normal on CBV and follow-up CT images.