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Fig 3. Blood flow and infarction. Data from awake monkeys in which an MCA was occluded.44 The open circles represent local blood flow in normal tissue, the open triangles are measurements in the periphery of the infarct, and the closed rectangles depict blood flow within the infarct. The dashed line approximates the infarction threshold; when the local CBF crosses this line, there is irreversible injury. Local CBF outside this line, but below normal levels (
20–25 mL/100 g per minute), represents the ischemic penumbra.
