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Fig 4. Plots demonstrate the correlation between the ratio of ischemic hemisphere mean integral value (area under the curve) of NAA (A, B) and LAC (C, D) with the control hemisphere mean integral value of NAA and the Spetzler score (A, C) and Mack scale (B, D) functional outcome measurements at 10 days postischemia. There is a positive correlation shown in (A) and (B) for the metabolite NAA on both scoring systems, with higher fractional NAA correlating with better functional outcome (higher scores). In contrast, there is a strong negative correlation observed for LAC (C, -D), with higher fractional LAC ratios being associated with lower (worse) functional outcome scores (Spetzler, r2 = 0.72; Mack, r2 = 0.73).
