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Fig 1. MR images of a 2-year-old girl with a germ-line mutation of the hSNF5/INI1 gene and AT/RT in the vermis extending into the fourth ventricle.
A, Sagittal (TR/TE, 520/10) MR image shows the tumor to have intermediate and low signal intensity. The tumor invades the dorsal brain stem.
B, Axial (TR/TE, 5700/90) MR image shows the tumor to have heterogeneous intermediate-to-slightly-high signal intensity that is slightly hyperintense relative to gray matter, as well as zones of high signal intensity representing cystic/necrotic regions. Abnormal high signal intensity is also seen in the dorsal pons and left middle cerebellar peduncle, consistent with tumor invasion.
C, Axial (TR/TE, 680/22) MR image shows the tumor to have solid-enhancing and nonenhancing cystic/necrotic components. Irregular enhancing margins of the lesion are seen at the dorsal pons and left middle cerebellar peduncle, consistent with tumor invasion. This patient died 1.6 years after diagnosis from locally recurrent and disseminated tumor.
D, Axial CT image shows the solid portion of the AT/RT to have attenuation slightly higher than that of gray matter. Low-attenuation cystic/necrotic zones and several tiny calcifications are also present.
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