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Fig 5. Graph shows the effects of acute administration of TS-011 (1 mg/kg IV) on the diameter of the basilar artery of dogs, with documented evidence of delayed vasospasm after induction of the dual hemorrhage model of SAH. Paired angiograms were obtained in 9 dogs before and 1 hour after administration of TS-011. The asterisk indicates a significant difference in the diameter of the basilar artery versus that of the corresponding control value measured before administration of TS-011.