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Fig 1. Histogram analyses. Representative measurements of a control subject, a patient with juvenile-onset DRPLA, and a patient with adult-onset DRPLA are plotted (left). The peak heights were lower and peak locations higher in patients with DRPLA than in controls, with greater changes in adult-onset disease. Mean ADC values were significantly higher in patients with DRPLA (P) than in age- and sex-matched control subjects (C) (center). Mean ADC values were higher in adult-onset disease than in juvenile-onset disease (right).
