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Fig 2. Region of interest (ROI) analyses. ROIs were set in the globus pallidus (white arrowhead), thalamus (black arrowhead), temporal white matter (white arrow), and cerebellum (black arrow). The ADC values in the globus pallidus and cerebellum of patients with DRPLA (P) were significantly higher than those of age- and sex-matched control subjects (C). In contrast, the ADC values did not differ in the thalamus. ADC values in the white matter were higher in patients with adult-onset disease (AP) than in age-matched control subjects (AC). ADC values in the white matter did not differ significantly between patients with juvenile-onset disease (JP) and age- and sex-matched control subjects (JC).
