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Fig 3. Gross and microscopic evaluation of resected aneurysms:
A, Macroscopic view of the aneurysm orifice from the arterial lumen. The former aneurysm neck is completely covered with a fibrous tissue layer.
B, Microscopic view of the carotid artery harboring the embolized aneurysm reveals a smooth transition from the arterial wall surface to the newly formed membrane (arrows), which consists of fibrous connective tissue (hematoxylin-eosin; original magnification, 20x). C, carotid artery wall; M, connective tissue membrane; S, suture; P, polymer inclusions.
C, Neointima formation consisting of fibroblasts covered by a single layer of endothelial cells (arrows). Note the disruption of the internal elastic lamina within the neointima (Elastica van Gieson; original magnification, 100x). C, carotid artery wall; M, connective tissue membrane.
D, Intra-aneurysmal inflammatory response consists mostly of lymphocytes and histiocytes (IR). Note numerous multinucleated foreign giant cells (GC) surrounding the eosinophilic embolic material (P) as well as many inflammatory cells within the polymer fragments (hematoxylin-eosin; original magnification, 100x).
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