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Fig 3. Verapamil alters Mn2+ uptake in the olfactory bulb and pituitary gland. Change in intensity with time in the olfactory bulb was modulated by different doses of verapamil injected intranasally before MnCl2 administration (A). In the same subjects, VOI in the pituitary indicates that low- and medium-dose verapamil have a nearly identical effect on uptake; however, uptake remains virtually extinct with a high dose (B). The vertical axis represents normalized intensity for VOIs in the right olfactory bulb and in the pituitary gland that have been subtracted from baseline values. The horizontal axis is time in hours postinjection of MnCl2. Error bars show the SD of mean change in intensity. The asterisk indicates differences that reached statistical significance (P 
.05).
