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Fig 4. Patterns of lesion formation, comparing acute and subacute durations of activity. Examples of 3 lesions of different sizes, with columns showing different sections from superior to inferior (left to right). Lesion 1 was small extending only over 2 sections; lesion 3 was much larger and was visible on 9 sections (section thickness, 3 mm). Lesions are shown at individual scale (see size bar for each lesion). Rows show duration in weeks of acute (A) and subacute phases (B), as defined in Fig. 2. Analogous concentric patterns and a faster recovery at the periphery of the lesion are apparent. Note that the duration of the acute phase is far shorter (4 weeks or less) than that of the subacute phase (up to 20 weeks).
