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Fig 2. WHO grade III glioma in a 39-year-old woman. A, Postcontrast T1-weighted axial image showing a large heterogeneously enhancing left temporal mass lesion with significant mass effect. B, Corresponding CBV map showing elevated blood volume (nCBV = 2.61). C, CBF map showing increased blood flow (nCBF = 1.65). D, MTT map showing decreased MTT (nMTT = 1.68) within the tumor. Also note the mismatch between areas of increased blood volume/blood flow on the CBV/CBF maps and the areas of gadolinium enhancement.