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Fig 2. Same as Fig 1, except that the average individual rates of WBNAA decline per year, R2, were estimated for disease duration from FS, 
Y2, as defined by Equations (2) and (5b). The vertical dotted lines at R1 = 0 and 1.7 mmol/L/y partition the cohort into stable (
), moderate (
), and rapid (
) decline rates according to criteria defined in the text.23
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