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Fig 1. The human chromosome. A, Schematic drawing of a human chromosome in metaphase of the cell cycle. The chromosome consists of chromatin, which is made of a molecule of DNA complexly coiled around a protein frame, forming a chromatid. Paired chromatids, consisting of identical molecules of DNA, are joined at the centromere. B, Normal male karyotype showing the 23 pairs of human chromosomes for a total of 46 arranged in 8 groups based on size and shape. Karyotype courtesy of Colorado Genetic Laboratory, University of Colorado Health Sciences Center, Denver.
