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Fig 2. Angiographic image of mouse cerebral artery. A, Macroimage of the right brain hemisphere. The cerebral arteries (arrows), but not cerebral veins, are filled with the barium sulfate. B, Cerebral microangiogram (90° caudal projection) with a mammographic soft x-ray machine. Mammography enables visualization of small cerebral arteries and penetrating intracerebral arteries, but the image is not sufficient to evaluate pathologic changes. C and D, Cerebral angiograms obtained by SR. Note that small cerebral vessels, including penetrating intracerebral arteries, are clearly visualized. Microvascular structures, such as orthogonal branching of penetrating intracerebral arteries from the cortical artery, are clearly observed by the enlarged SR imaging (D). E, Coronal section of a cerebral microangiogram. Two distinct penetrating intracerebral arteries, superficial penetrating arteries and deep penetrating arteries (arrow), are clearly observed by the SR image. Scale bars: 1 mm (A and B), 0.5 mm (C and E), and 250 µm (D).
