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Fig 4. Visualization of selected surface features by LOOCV experiment when the patch size is 50 x 100 in patients with AD compared with healthy control subjects. The first row shows the left and right hippocampi from the top view, whereas the second row shows them from the bottom view. Boundaries between the 3 zones of the hippocampal surface (ie, LZ, SZ, and IMZ) are drawn in black. LZ represents the lateral zone of the hippocampal surface, and approximates the CA1 subfield. SZ represents the superior zone approximating the combined CA2, CA3, and CA4 subfields and the gyrus dentatus, and IMZ represents the inferior-medial zone approximating the subiculum. All 3 zones are labeled. The white subregions represent no differences in the hippocampal surfaces between patients with AD and healthy control subjects. The significance of features is measured by the repeatability in the subsets. The more significant features are shaded on the purple-red hue scale shown in the third row. The purple represents lower significance, and the red represents higher significance.
