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Fig 1. Patient 1. Morphologic MR imaging. A and B, respectively, Axial 3D-T1 (TR=13.3 ms, TE=4.2 ms) and axial 3D-T2 (TR=3000 ms, TE=154 ms)-weighted MR images show multiple confluent oval well-defined lesions, isointense to CSF, in the left superior (F1) and inferior (F2) frontal gyri, a portion of the left precentral gyrus, the anterior left cingulate gyrus, and the corpus callosum. These cystic dilations have a mild mass effect, inducing a displacement of the cortical ribbon. C, fMRI (motor task of the right hand) shows a cortical activation in the left motor supplementary area (white curved arrow) in Broadmann areas 4 (white arrowhead) and 6 (white arrow). D, There is also a symmetric cortical activation when the left hand is stimulated. E, The tractography shows a decrease of white matter fibers in the pathologic areas (white arrowhead) compared with the healthy side.
