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Fig 4. Reproducibility of SSEG and CSEG methods: Bland-Altman analysis in 10 patients (scan-rescan group). The solid line and the 2 dotted lines represent the mean ± 1.96 SD (95% confidence interval) of the difference of rescan lesion volume and baseline lesion volume, respectively. For both measurements, we use the same baseline lesion volume measured by CSEG. A, For the CSEG measurement, we used the baseline and rescan lesion volumes. B, For the SSEG measurement, the rescan lesion volume is the sum of baseline lesion volume (measured by CSEG) and the net change in lesion volume measured by the SSEG method. We see that the SSEG method has smaller confidence intervals, which indicate greater reproducibility.
