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Fig 2. Measured signal intensity (SI) as a function of the dilution factor for TR = 100 and TE = 14 msec. At 1.5T (A) and at 3T (B), there are low signal intensities measured at low dilution factors/high concentrations, reflecting R2 relaxivity and T2(*) effects of contrast. At higher dilution factors/lower concentrations, T1 shortening effects predominate. Physiologic concentrations for T1WI range between the 2 dashed lines, 1:000–1:4000. Concentrations for PWI range below the dotted line, 1:200.