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Fig 3. Macroscopic and pathologic findings of aneurysm with complete angiographic occlusion at 3 months after coil embolization. A, Photograph of aneurysmal neck en face. Note complete closure of the neck by a translucent layer of membrane tissue. B, Low-magnification overview of an axial aneurysm section showing a continuous layer of smooth muscle (SM) 
-actin+ cells completely sealing the neck of the aneurysm. At higher magnification (C and D are magnifications of the inset c,d in B), closed corner (arrows in B and C) shows aligned SM -actin+ cells covered by a single layer of NOS+ endothelial cells. E, The same neointimal layer is continuous, isolating the aneurysm from the circulation. F, SM -actin immunostaining of atrophied aneurysmal wall. Sections are hematoxylin-counterstained (scale bar: 1000 µm for B; 200 µm for C–F; 40 µm for insets in C and D).
