AJDRAJNR - American Journal of Neuroradiology

Published ahead of print on February 22, 2008
doi: 10.3174/ajnr.A1050
This Article
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
ajnr.A1050v1
29/4/e15    most recent
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Prosch, H.
Right arrow Articles by Prayer, D.
Right arrow Search for Related Content
PubMed
Right arrow Articles by Prosch, H.
Right arrow Articles by Prayer, D.

American Journal of Neuroradiology 29:e15, April 2008
© 2008 American Society of Neuroradiology

Letter

Reply:

H. Proscha

a Otto Wagner Hospital
Department of Radiology
Vienna, Austria

N. Groisb

b Children's Cancer Research Institute
Vienna, Austria

D. Prayerc

c Medical University of Vienna
Division of Neuroradiology
Vienna, Austria

Thank you for your interest in our article1 and for sharing your interesting case. The proton MR spectra fit well with that of another patient with neurodegenerative Langerhans cell histiocytosis (ND-LCH) previously reported.2 Decreased N-acetylaspartate peak accompanied by increased choline in the area of cerebellar signal intensity alterations supports the concept of a neurodegenerative process. Further studies are necessary to evaluate the sensitivity and specificity of 1H-MR spectroscopy in ND-LCH.

References

  1. Prosch H, Grois N, Wnorowski M, et al. Long-term MR imaging course of neurodegenerative Langerhans cell histiocytosis. AJNR Am J Neuroradiol 2007;28:1022–28[Abstract/Free Full Text]

  2. Steiner M, Prayer D, Asenbaum S, et al. Modern imaging methods for the assessment of Langerhans’ cell histiocytosis-associated neurodegenerative syndrome: case report. J Child Neurol 2005;20:253–57[Abstract/Free Full Text]





This Article
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
ajnr.A1050v1
29/4/e15    most recent
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Prosch, H.
Right arrow Articles by Prayer, D.
Right arrow Search for Related Content
PubMed
Right arrow Articles by Prosch, H.
Right arrow Articles by Prayer, D.

Copyright © 2009 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X