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Fig 2. Signal modulation of in vivo PRESS spectra of anaplastic astrocytoma (i) and DIBSG (ii + iii) acquired with different TE. In vivo spectra acquired at TE of 35 ms (A), 144 ms (B), and 316 ms (C) from the same ROI are compared with spectra obtained from a citrate model solution at the same conditions. The complex signal centered at 2.6 ppm in tumor spectra shows the same J-modulation as citrate. At a TE of 316 ms, the center peaks of citrate are inverted.
