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Fig 1. A 75-year-old woman, who was being regularly seen by her neurologist for a gradual decline in cognitive function over a few years, was referred to the department of radiology for MR examination to rule out temporal lobe atrophy, which could indicate Alzheimer disease. On FLAIR, multiple WMLs are seen, and on DWIs, there is a single focus of hyperintensity among these multiple WMLs at the left centrum semiovale (black arrows). The lesion also has a reduced ADC (white arrows), which suggests that this is a relatively acute lesion. The presence of minimal temporal lobe atrophy (not shown) does not support a diagnosis of Alzheimer disease.
