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Fig 2. Rendering of the simple t test and full model (corrected for age, sex, NYU, and global gray matter) between MCI converters and nonconverters. The big yellow area on the left hemisphere denotes less gray matter (more atrophy) in the converters group, compared with nonconverters, as captured by the t test. After correcting for age, sex, global gray matter atrophy, and a neuropsychological measure that is a good predictor of conversion to AD (NYU), atrophy in the left lateral temporal lobe and left parietal regions remains statistically significant, depicted as red. Results were thresholded at P = .001 uncorrected for multiple comparisons for display purposes.
