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Fig 4. T2-weighted MR, selected spectra, and metabolic images of Cho, Cr, NAA, and lactate (Lac) in a typical patient with Canavan disease. NAA is higher than normal in both white and gray matter regions. Note lower (ie, more normal) NAA levels, as seen in voxel 2 and in the NAA metabolic image, in the deeper white matter where there is less signal-intensity abnormality on the T2-weighted MR image. PPM indicates parts per million.
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