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Fig 2. 1H-MR-spectroscopy water-suppressed proton spectra of an 8-mL voxel located in the parietal region including predominantly normal-appearing white matter in a patient with cirrhosis before (left) and after (right) liver transplantation, recorded with a stimulated echo acquisition mode pulse sequence (TR/TE, 1600/20 ms; acquisitions, 256). The main resonances correspond to N-acetylaspartate (NAA, 2.0 ppm), glutamine/glutamate (Glx, 2.1–2.5 ppm), creatine/phosphocreatine (Cr, 3.02 ppm), choline-containing compounds (Cho, 3.2 ppm), and myo-inositol (Ins, 3.55 ppm). The initial spectrum shows an increase in the glutamate/glutamine region and a decrease in the myo-inositol and choline resonances. These abnormalities normalized after liver transplantation. Normal NAA indices are seen in both examinations.
