AJDRAJNR - American Journal of Neuroradiology

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American Journal of Neuroradiology 2008;29:363.

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American Journal of Neuroradiology
DOI 10.3174/ajnr.A0802

BRAIN

Comparison of Optimized and Standard Diffusion-Weighted Imaging at 1.5T for the Detection of Acute Lesions in Patients with Transient Ischemic Attack

A. Bertrand, C. Oppenheim, C. Lamy, S. Rodrigo, O. Naggara, J.L. Mas and J.F. Meder

From the Departments of Neuroradiology (A.B., C.O., S.R., O.N., J.F.M.) and Neurology (C.L., J.L.M.), Université Paris Descartes, Centre Hospitalier Sainte-Anne, Paris, France.

Please address correspondence to Catherine Oppenheim, Departement of Neuroradiology, Université Paris Descartes, Centre Hospitalier Sainte-Anne, 1 rue Cabanis, 75014 Paris, France; e-mail: c.oppenheim{at}ch-sainte-anne.fr

SUMMARY: The high rate of normal diffusion-weighted imaging (DWI) in patients with transient ischemic attack (TIA) raises the question as to its sensitivity for detecting small ischemic lesions. We compared standard and optimized DWI in 36 consecutive patients with TIA. Optimized DWI was positive in more patients than standard DWI (19 versus 16; P < .001) and showed more lesions (56 versus 42; P = .002). At 1.5T, optimizing DWI decreases the rate of false-negative DWI in patients with TIA.






Copyright © 2009 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X