AJDRAJNR - American Journal of Neuroradiology

Publication Preview: Published January 17, 2008

American Journal of Neuroradiology 2008;29:828.

This Article
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
ajnr.A0966v1
29/4/828    most recent
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Arnold, R.
Right arrow Articles by Gaisie, G.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Arnold, R.
Right arrow Articles by Gaisie, G.

American Journal of Neuroradiology
DOI 10.3174/ajnr.A0966

PEDIATRICS

Substantia Nigra MR Imaging Signal Changes and Cardiomyopathy Following Prenatal Exposure to Cocaine and Heroin

R. Arnold, C. Johnson, B. McNulty and G. Gaisie

From the Departments of Diagnostic Radiology (R.A., C.J.) and Neuroradiology (B.N.), Northeastern Ohio Universities College of Medicine-Canton Affiliated Hospitals, Canton, Ohio; and the Department of Pediatric Radiology (G.G.), Akron Children's Hospital, Akron, Ohio.

Please address correspondence to Ryan Arnold, MD, Department of Diagnostic Radiology, Northeastern Ohio Universities College of Medicine-Canton Affiliated Hospitals, 2600 Sixth St SW, Canton, OH 44710; e-mail: ryanradiology{at}gmail.com

SUMMARY: Exposure to cocaine in utero results in behavioral and neurodevelopmental abnormalities that persist into adulthood. Conventional MR imaging has generally failed to reveal the expected structural lesions to explain these clinical findings. We report a case of focal MR imaging signal-intensity changes in the substantia nigra, locus ceruleus, and other selected nerve tracts and nuclei in a child exposed prenatally to cocaine and other drugs. The patient also had dilated cardiomyopathy.






Copyright © 2008 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X