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AJNR - American Journal of Neuroradiology

Publication Preview: Published February 22, 2008

American Journal of Neuroradiology 2008;29:941.

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American Journal of Neuroradiology
DOI 10.3174/ajnr.A1016

BRAIN

Sequential Pituitary Magnetic Resonance Imaging in Sheehan Syndrome: Report of 2 Cases

J. Kaplun, C. Fratila, A. Ferenczi, W.C. Yang, G. Lantos, A.M. Fleckman and U.K. Schubart

From the Departments of Medicine (J.K., A.F., A.M.F.) and Radiology (W.C.Y.), Beth Israel Medical Center, University Hospital and Manhattan Campus for the Albert Einstein College of Medicine, New York, NY; and Departments of Medicine (C.F., U.K.S.) and Radiology (G.L.), Jacobi Medical Center, Bronx, NY.

Please address correspondence to George Lantos, MD, Department of Radiology, Jacobi Medical Center, 1400 Pelham Parkway South, Bronx, NY 10461; e-mail: lantosg{at}post.harvard.edu

SUMMARY: We present the evolution of pituitary changes in the cases of 2 patients with Sheehan syndrome as assessed by MR imaging. Both patients had severe postpartum hemorrhage, symptoms of pituitary gland apoplexy, and hypopituitarism. Sequential MR imaging demonstrated evidence of ischemic infarct in the pituitary gland with enlargement followed by gradual shrinkage during several months, to pituitary atrophy.