AJDRAJNR - American Journal of Neuroradiology

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American Journal of Neuroradiology 2008;29:843.

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American Journal of Neuroradiology
DOI 10.3174/ajnr.A1052

PHYSICS REVIEW

Diffusion Tensor MR Imaging and Fiber Tractography: Technical Considerations

P. Mukherjee, S.W. Chung, J.I. Berman, C.P. Hess and R.G. Henry

From the Department of Radiology, University of California, San Francisco, San Francisco, Calif.

Please address correspondence to Pratik Mukherjee, MD, PhD, Department of Radiology, Box 0628, University of California, San Francisco, 505 Parnassus Ave, L-358, San Francisco, CA 94143-0628; e-mail: pratik{at}radiology.ucsf.edu

SUMMARY: This second article of the 2-part review builds on the theoretic background provided by the first article to cover the major technical factors that affect image quality in diffusion imaging, including the acquisition sequence, magnet field strength, gradient amplitude, and slew rate as well as multichannel radio-frequency coils and parallel imaging. The sources of many common diffusion image artifacts are also explored in detail. The emphasis is on optimizing these technical factors for state-of-the-art diffusion-weighted imaging and diffusion tensor imaging (DTI) based on the best available evidence in the literature. An overview of current methods for quantitative analysis of DTI data and fiber tractography in clinical research is also provided.




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Copyright © 2009 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X