AJDRAJNR - American Journal of Neuroradiology

Publication Preview: Published May 22, 2008

American Journal of Neuroradiology 2008;29:1561.

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HEAD & NECK

Retropharyngeal Lymph Node Metastasis From Esthesioneuroblastoma: A Review of the Therapeutic and Prognostic Implications

L.V. Zollinger, R.H. Wiggins, III, R.S. Cornelius and C.D. Phillips

From the Departments of Radiology (L.V.Z.) and Radiology, Otolaryngology, Head and Neck Surgery, and Biomedical Informatics (R.H.W.); Head and Neck Neuroradiology, University of Utah School of Medicine, Salt Lake City, Ut; Department of Radiology, Section of Neuroradiology (R.S.C.), University of Cincinnati Medical Center, Cincinnati, Ohio; and Department of Radiology, Section of Neuroradiology (C.D.P.), University of Virginia School of Medicine, Charlottesville, Va.

Please address correspondence to Lauren V. Zollinger, MD, MPH, Department of Radiology, University of Utah School of Medicine, 30 North 1900 East #1A071, Salt Lake City, UT 84132; e-mail: Lauren.zollinger{at}hsc.utah.edu

SUMMARY: Esthesioneuroblastoma (ENB) is a malignant neoplasm of the olfactory epithelium. Metastasis of ENBs to retropharyngeal lymph nodes is an important finding on imaging examinations that alters staging and treatment. A total of 17 cases of ENB from 3 institutions were evaluated. The CT and MR imaging findings from the cases of 4 patients with ENB with retropharyngeal metastatic disease are reviewed. The vector of spread, staging, and treatment implications are discussed.