American Journal of Neuroradiology 2009;30:77.
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American Journal of Neuroradiology
DOI 10.3174/ajnr.A1263
HEAD & NECK
Unusual Radiographic Appearance of Drug-Induced Pharyngeal Angioedema and Differential Considerations
From the University of Washington (S.P.R., B.E.L.), Seattle, Wash; and University of Washington's Children's Hospital and Regional Medical Center (S.P.), Seattle, Wash.
Please address correspondence to Sumit Pruthi, MD, R-5417–Radiology, Children's Hospital and Regional Medical Center (University of Washington), 4800 Sand Point Way NE, Seattle, WA 98105; e-mail: sumitp{at}u.washington.edu
SUMMARY: A 59-year-old woman treated chronically with enalapril, an angiotensin-converting enzyme inhibitor (ACE-I) presented with difficult swallowing and speaking. Although her symptoms were clinically consistent with an adverse angioedema reaction to the ACE-I, initial imaging was not entirely consistent with our conceptual understanding of angioedema. This case report will discuss the myriad possible imaging presentations of this disease, as well as the differential diagnosis for this atypical manifestation of ACE-I–induced angioedema.