AJDRAJNR - American Journal of Neuroradiology

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American Journal of Neuroradiology 2009;30:586.

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BRAIN

Posterior Reversible Encephalopathy Syndrome after Intravenous Caffeine for Post–Lumbar Puncture Headaches

G.A. Ortiz, N.A. Bianchi, M.P. Tiede and R.G. Bhatia

From the Departments of Neurology (G.A.O., N.A.B., M.P.T.) and Radiology (R.G.B.), University of Miami Miller School of Medicine, Jackson Memorial Hospital, Miami, Fla.

Please address correspondence to Gustavo A. Ortiz, MD, 1150 NW 14th St, Suite 603, Miami, FL 33136; e-mail: gortiz2{at}med.miami.edu

SUMMARY: A 33-year-old woman developed severe post–lumbar puncture headaches in the course of work-up for multiple sclerosis. Immediately after receiving treatment with intravenous caffeine, she became blind and experienced a generalized tonic-clonic seizure. Brain MR imaging then showed vasogenic parieto-occipital edema. She recovered clinically and radiologically within 72 hours. After 1 year of follow-up, there was no recurrence of symptoms or radiologic changes.