AJDRAJNR - American Journal of Neuroradiology

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American Journal of Neuroradiology 2009;30:769.

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American Journal of Neuroradiology
DOI 10.3174/ajnr.A1467

HEAD & NECK

MR Imaging Findings of the Uveal Schwannoma

J. Xian, X. Xu, Z. Wang, B. Yang, B. Li, F. Man, Q. Chen, J. Shi and Y. Zhang

From the Departments of Radiology (J.X., Z.W., B.Y., F.M., Q.C.) and Ophthalmology (X.X., B.L., J.S.), Capital Medical University, Beijing Tongren Hospital, Beijing, China; Department of Radiology (J.X., Y.Z.), Tianjin Medical University General Hospital, Tianjin, China, and Beijing Institute of Ophthalmology (X.X., B.L.), Beijing, China.

Please address correspondence to Zhenchang Wang, MD, Department of Radiology, Capital Medical University, Beijing Tongren Hospital, Beijing, China; and Bin Li, MD, Department of Ophthalmology, Capital Medical University, Beijing Tongren Hospital, Beijing, China; e-mail: cjr.xianjunfang{at}vip.163.com

BACKGROUND AND PURPOSE: Uveal schwannoma is a rare benign neoplastic proliferation of pure Schwann cells. The purpose of this study was to describe MR imaging features of uveal schwannoma.

MATERIALS AND METHODS: MR images in 6 female patients with uveal schwannoma confirmed by pathologic examination were retrospectively reviewed. MR imaging was performed in all 6 patients, with postcontrast T1-weighted imaging (T1WI) completed in all 6 patients and dynamic contrast-enhanced MR imaging, in 5. MR imaging findings of the tumor were evaluated with emphasis on the location, size, shape, margin, signal intensity, and pattern of enhancement.

RESULTS: The lesions appeared as solitary well-defined ovoid masses in the ciliochoroidal region in 5 patients and in the choroid in 1. With respect to the vitreous body, uveal schwannoma was hyperintense on T1WI spin-echo (SE) images in all 6 patients. The tumors were hypointense to the vitreous body on fast SE (FSE) T2-weighted images (T2WI) in 4 patients and isointense in 1. However, with respect to the brain, uveal schwannoma demonstrated isointensity on T1WI SE images in all 6 patients, isointensity on FSE T2WI images in 5 patients, and hyperintensity on T2WI SE images in 1. On postcontrast T1WI images, 3 patients showed markedly heterogeneous enhancement, and 3 showed markedly homogeneous enhancement.

CONCLUSIONS: Uveal schwannoma should be included in the differential diagnosis when an oval isointense mass relative to brain is seen in the ciliochoroidal region.






Copyright © 2009 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X