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Abstract

An experimental model to study contrast enhancement in MR imaging of the intervertebral disk.

C M Nguyen, K C Ho, S W Yu, V M Haughton and J A Strandt
American Journal of Neuroradiology July 1989, 10 (4) 811-814;
C M Nguyen
Department of Radiology, Medical College of Wisconsin, Froedtert Memorial Lutheran Hospital 53226.
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K C Ho
Department of Radiology, Medical College of Wisconsin, Froedtert Memorial Lutheran Hospital 53226.
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S W Yu
Department of Radiology, Medical College of Wisconsin, Froedtert Memorial Lutheran Hospital 53226.
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V M Haughton
Department of Radiology, Medical College of Wisconsin, Froedtert Memorial Lutheran Hospital 53226.
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J A Strandt
Department of Radiology, Medical College of Wisconsin, Froedtert Memorial Lutheran Hospital 53226.
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Abstract

MR imaging after IV gadolinium-DTPA administration has demonstrated contrast enhancement in traumatized lumbar intervertebral disks. To characterize the morbid anatomy that correlates with the contrast enhancement, we developed a canine model of traumatized intervertebral disks. Diskectomy was performed with a nucleotome and the spines were imaged biweekly with MR and Gd-DTPA. The spines were studied at necropsy, and their anatomic abnormalities correlated with contrast enhancement detected by MR imaging. Our preliminary results indicate that contrast enhancement occurs where granulation tissue develops in traumatized intervertebral disks.

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American Journal of Neuroradiology
Vol. 10, Issue 4
1 Jul 1989
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An experimental model to study contrast enhancement in MR imaging of the intervertebral disk.
C M Nguyen, K C Ho, S W Yu, V M Haughton, J A Strandt
American Journal of Neuroradiology Jul 1989, 10 (4) 811-814;

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An experimental model to study contrast enhancement in MR imaging of the intervertebral disk.
C M Nguyen, K C Ho, S W Yu, V M Haughton, J A Strandt
American Journal of Neuroradiology Jul 1989, 10 (4) 811-814;
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