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Abstract

Treatment of arteriovenous malformations of the brain with combined embolization and stereotactic radiosurgery: results after 1 and 2 years.

R C Dawson, R W Tarr, S T Hecht, C A Jungreis, L D Lunsford, R Coffey and J A Horton
American Journal of Neuroradiology September 1990, 11 (5) 857-864;
R C Dawson 3rd
Department of Radiology, University of Pittsburgh, Presbyterian-University Hospital, PA 15213.
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R W Tarr
Department of Radiology, University of Pittsburgh, Presbyterian-University Hospital, PA 15213.
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S T Hecht
Department of Radiology, University of Pittsburgh, Presbyterian-University Hospital, PA 15213.
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C A Jungreis
Department of Radiology, University of Pittsburgh, Presbyterian-University Hospital, PA 15213.
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L D Lunsford
Department of Radiology, University of Pittsburgh, Presbyterian-University Hospital, PA 15213.
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R Coffey
Department of Radiology, University of Pittsburgh, Presbyterian-University Hospital, PA 15213.
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J A Horton
Department of Radiology, University of Pittsburgh, Presbyterian-University Hospital, PA 15213.
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Abstract

Seven patients with large arteriovenous malformations (AVMs) of the brain were selected for combined therapy with particulate embolization, followed by radiosurgery of the residual nidus. The goal of embolization was to reduce the patient nidus to a size that facilitated successful stereotactic radiosurgery. Angiograms obtained 1 and 2 years after radiosurgery were evaluated for changes in nidus size, flow rate, and feeding and draining vessels. One year after stereotactic radiosurgery, one AVM was angiographically undetectable. Three other AVMs demonstrated a volume reduction of greater than 50%, in addition to decreased shunt speed and altered angioarchitecture at 1-year follow-up. At 2-year follow-ups, two of seven AVMs were cured, and an additional two of seven had a greater than 98% reduction in nidus volume. Although one patient experienced a transient deficit from embolotherapy, none of our patients suffered a new neurologic deficit or a hemorrhage during the follow-up period. Our data support the efficacy of combined embolotherapy and radiosurgery for definitive therapy of selected large AVMs of the brain.

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American Journal of Neuroradiology
Vol. 11, Issue 5
1 Sep 1990
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Treatment of arteriovenous malformations of the brain with combined embolization and stereotactic radiosurgery: results after 1 and 2 years.
R C Dawson, R W Tarr, S T Hecht, C A Jungreis, L D Lunsford, R Coffey, J A Horton
American Journal of Neuroradiology Sep 1990, 11 (5) 857-864;

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Treatment of arteriovenous malformations of the brain with combined embolization and stereotactic radiosurgery: results after 1 and 2 years.
R C Dawson, R W Tarr, S T Hecht, C A Jungreis, L D Lunsford, R Coffey, J A Horton
American Journal of Neuroradiology Sep 1990, 11 (5) 857-864;
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