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Abstract

Interuncal distance as a measure of hippocampal atrophy: normative data on axial MR imaging.

P M Doraiswamy, W M McDonald, L Patterson, M M Husain, G S Figiel, O B Boyko and K R Krishnan
American Journal of Neuroradiology January 1993, 14 (1) 141-143;
P M Doraiswamy
Department of Psychiatry, Duke University Medical Center, Durham, NC 27710.
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W M McDonald
Department of Psychiatry, Duke University Medical Center, Durham, NC 27710.
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L Patterson
Department of Psychiatry, Duke University Medical Center, Durham, NC 27710.
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M M Husain
Department of Psychiatry, Duke University Medical Center, Durham, NC 27710.
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G S Figiel
Department of Psychiatry, Duke University Medical Center, Durham, NC 27710.
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O B Boyko
Department of Psychiatry, Duke University Medical Center, Durham, NC 27710.
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K R Krishnan
Department of Psychiatry, Duke University Medical Center, Durham, NC 27710.
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Abstract

PURPOSE To assess the effects of age and gender on the interuncal distance measured from MR images.

METHODS High-field strength MR images (axial) of 75 volunteers, 21-82 years old and free of neurologic disorders, were used to measure the interuncal distance.

RESULTS The interuncal distance increased with age (r = 0.66, P < .0001). The mean (SD) interuncal distance for all subjects was 21.4 (4) mm with a range of 12 to 29 mm.

CONCLUSIONS The interuncal distance in healthy subjects is unlikely to exceed 30 mm. Our data may be of clinical significance in view of a previous report stating that the interuncal distance may be enlarged in pathologic hippocampal degeneration, such as in patients with Alzheimer disease.

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American Journal of Neuroradiology
Vol. 14, Issue 1
1 Jan 1993
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Interuncal distance as a measure of hippocampal atrophy: normative data on axial MR imaging.
P M Doraiswamy, W M McDonald, L Patterson, M M Husain, G S Figiel, O B Boyko, K R Krishnan
American Journal of Neuroradiology Jan 1993, 14 (1) 141-143;

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Interuncal distance as a measure of hippocampal atrophy: normative data on axial MR imaging.
P M Doraiswamy, W M McDonald, L Patterson, M M Husain, G S Figiel, O B Boyko, K R Krishnan
American Journal of Neuroradiology Jan 1993, 14 (1) 141-143;
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