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Abstract

Kallmann syndrome: MR findings.

J R Knorr, R L Ragland, R S Brown and N Gelber
American Journal of Neuroradiology July 1993, 14 (4) 845-851;
J R Knorr
Department of Radiology, University of Massachusetts Medical Center, Worcester 01655.
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R L Ragland
Department of Radiology, University of Massachusetts Medical Center, Worcester 01655.
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R S Brown
Department of Radiology, University of Massachusetts Medical Center, Worcester 01655.
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N Gelber
Department of Radiology, University of Massachusetts Medical Center, Worcester 01655.
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Abstract

PURPOSE To evaluate patients with known hypogonadotropic hypogonadism, some with known anosmia, for defective rhinocephalon development that resulted in olfactory tract abnormalities, an affliction known as Kallmann syndrome.

METHODS Six patients who clinically had hypogonadotropic hypogonadism were examined by MR. Thin coronal images of the interior frontal region were used to determine presence or absence of olfactory tract and to evaluate the olfactory sulci.

RESULTS Olfactory tracts were not seen in three of the six cases; two of which had hypoplastic olfactory sulci.

CONCLUSIONS T1-weighted MR examination of the inferior frontal region in the coronal plane can help determine whether a patient with hypogonadotropic hypogonadism, with or without clinically evident anosmia, is afflicted with Kallmann syndrome.

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American Journal of Neuroradiology
Vol. 14, Issue 4
1 Jul 1993
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Kallmann syndrome: MR findings.
J R Knorr, R L Ragland, R S Brown, N Gelber
American Journal of Neuroradiology Jul 1993, 14 (4) 845-851;

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Kallmann syndrome: MR findings.
J R Knorr, R L Ragland, R S Brown, N Gelber
American Journal of Neuroradiology Jul 1993, 14 (4) 845-851;
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  • Biochemical and MRI findings of Kallmann's syndrome
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  • PEDIATRIC NEURORADIOLOGY
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