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Abstract

Characteristics of ethylene vinyl alcohol copolymer (EVAL) mixtures.

K Yamashita, W Taki, H Iwata, I Nakahara, S Nishi, A Sadato, K Matsumoto and H Kikuchi
American Journal of Neuroradiology June 1994, 15 (6) 1103-1105;
K Yamashita
Department of Neurosurgery, Faculty of Medicine, Kyoto University, Japan.
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W Taki
Department of Neurosurgery, Faculty of Medicine, Kyoto University, Japan.
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H Iwata
Department of Neurosurgery, Faculty of Medicine, Kyoto University, Japan.
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I Nakahara
Department of Neurosurgery, Faculty of Medicine, Kyoto University, Japan.
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S Nishi
Department of Neurosurgery, Faculty of Medicine, Kyoto University, Japan.
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A Sadato
Department of Neurosurgery, Faculty of Medicine, Kyoto University, Japan.
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K Matsumoto
Department of Neurosurgery, Faculty of Medicine, Kyoto University, Japan.
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H Kikuchi
Department of Neurosurgery, Faculty of Medicine, Kyoto University, Japan.
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Abstract

PURPOSE To determine physical characteristics of mixtures of ethylene vinyl alcohol copolymer (EVAL) and metrizamide dissolved in dimethyl sulfoxide, liquid materials developed for embolization of arteriovenous malformations.

METHODS EVAL and dimethyl sulfoxide were mixed in various proportions and sterilized. The viscosity and density of each mixture was measured. Precipitation times were determined by dropping the mixtures into saline or human blood. The mixtures were filtered and the filtrates weighed.

RESULTS Densities and viscosities of the various mixtures differed significantly, proportionally to the concentration of EVAL. Precipitation times also differed significantly, in inverse proportion to the concentration of EVAL. Temperature and aqueous solution did not affect precipitation times significantly. The weight of the filtrate significantly increased with time but was constant for each precipitation time. Temperature significantly affected filtrate weight; aqueous solution did not.

CONCLUSIONS Because of their different physical properties, the various EVAL mixtures are suited to embolizing different types of arteriovenous malformations.

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American Journal of Neuroradiology
Vol. 15, Issue 6
1 Jun 1994
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Characteristics of ethylene vinyl alcohol copolymer (EVAL) mixtures.
K Yamashita, W Taki, H Iwata, I Nakahara, S Nishi, A Sadato, K Matsumoto, H Kikuchi
American Journal of Neuroradiology Jun 1994, 15 (6) 1103-1105;

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Characteristics of ethylene vinyl alcohol copolymer (EVAL) mixtures.
K Yamashita, W Taki, H Iwata, I Nakahara, S Nishi, A Sadato, K Matsumoto, H Kikuchi
American Journal of Neuroradiology Jun 1994, 15 (6) 1103-1105;
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